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死亡与新生:关于小胶质细胞的哲学(2021年神经科学学会小胶质细胞与神经免疫学研讨会报告 重庆 PB 20210917)
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2021年神经科学学会小胶质细胞与神经免疫学研讨会的报告视频 重庆 PB 20210917 最近论文刚刚接收,所以该报告可以上传公布。详细信息: 本视频涉及的主要研究工作如下,其中第4篇为本报告的主体: 1) Huang Y., Xu Z., Xiong S., Sun F., Qin G., Hu G., Wang J., Zhao L., Zhang C., Liang Y.X., Wu T, Lu Z, Humayun M.S., So K.F., Pan Y., Li N., Yuan T.F.*, Rao Y.*, and Peng B.* (2018) Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion. Nature Neuroscience 21, 530-540. 2) Rao Y.*, Du S., Yang B., Wang Y., Li Y., Li R., Zhou T., Du X., He Y., Wang Y., Zhou X., Yuan T.-F.*, Mao Y.* and Peng B.* (2021) NeuroD1 induces microglial apoptosis and cannot induce microglia-to-neuron cross-lineage reprogramming, Neuron 109, 4094-4108.e4095. 3) Xu Z., Rao Y., Huang Y., Zhou T., Feng R., Xiong S., Yuan T.F., Qin S., Lu Y., Zhou X., Li X., Qin B., Mao Y., and Peng B.* (2020) Efficient strategies for microglia replacement in the central nervous system. Cell Reports 32, 108041. 4) Zhou T., Li Y., Li X., Zeng F., Rao Y., He Y., Wang Y., Liu M., Li D., Xu Z., Zhou X., Du S., Niu F., Peng J., Mei X., Ji S.-J., Shu Y., Lu W., Guo F., Wu T., Yuan T.-F., Mao Y. and Peng B.* (2022) Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice. Nature Communications (in press).
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